US Panel Recommends Johnson & Johnson Vaccine Booster With 2-Month Gap


Covid Vaccine: Emergency use authorization for J&J booster should follow within days to weeks.

Washington:

- Advertisement -

A high level panel of US medical experts voted unanimously Friday to recommend authorizing a second shot of the Johnson & Johnson Covid vaccine.

The decision will help end a sense of limbo for 15 million Americans who received the first dose but were worried whether it was enough to protect them, particularly after the rise of the Delta variant.

- Advertisement -

The committee members, convened by the Food and Drug Administration (FDA), agreed with the pharmaceutical company that safety and efficacy evidence favored a second dose.

The recommendation may be tweaked further by the FDA and by the Centers for Disease Control and Prevention (CDC), and an emergency use authorization should follow within days to weeks.

Several of the independent experts suggested that though J&J had applied to authorize a booster, a second J&J vaccine should in fact be regarded as an “additional” dose needed to achieve full vaccination.

- Advertisement -

“I think this frankly was always a two-dose vaccine. It’s hard to recommend this as a one-dose vaccine,” said Paul Offit, a vaccine expert from Children’s Hospital of Philadelphia.

The panel was also asked to discuss, but not to vote on, the question of so-called “mix and match” boosting, in which a person receives a different brand or type of vaccine as a booster than that used for the initial dose.

But FDA scientist Peter Marks said “it’s possible” that question will be voted on in future.

A preliminary study this week showed that people who have received the J&J vaccine may benefit from a booster dose of a different, messenger-RNA vaccine such as Pfizer or Moderna.

The single shot J&J vaccine was never as effective as its double-shot mRNA counterparts, but some evidence suggests it is less susceptible to waning than Pfizer and Moderna, because of the viral vector technology behind it.

Nevertheless, the company presented data showing efficacy against symptomatic Covid rose from 70 to 94 percent in a US trial after a second dose given two months after the first, similar to figures associated with mRNA vaccines.

Friday’s meeting came after the same panel voted Thursday to authorize a booster dose of Moderna’s vaccine for at-risk groups.

In that meeting, the panel decided to authorize a booster dose of Moderna for the over-65s, people aged between 18 and 64 who are at a higher risk of developing a severe version of the coronavirus, and those whose work may involve frequent exposure to the virus.

A similar decision was already reached for the Pfizer vaccine several weeks earlier, with experts concerned a booster might not be suitable for everyone, especially younger males at risk of developing myocarditis (heart inflammation) as a side effect.

But the J&J decision applies more broadly, to everyone over 18 who received the first shot of the vaccine at least two months earlier.

Serious but extremely rare safety concerns include blood clotting with low platelets, particularly in younger women, and Guillain-Barre Syndrome, a rare immune disorder that causes muscle weakness and sometimes temporary paralysis.

(This story has not been edited by NDTV staff and is auto-generated from a syndicated feed.)


Source Link

- Advertisement -

Share

Latest Updates

5 Yoga Poses for back pain

New Delhi: Back pain affects people of all age groups and is one of the world’s leading causes of disability. Back pain can...

Josephine Baker Enters France Pantheon – Deadline

Legendary Jazz Age performer and civil rights activist Josephine Baker made history today as the first Black woman to enter France’s hallowed Panthéon....

‘Flee’ Uses Animation To Tell Dramatic Story Of Gay Afghan Refugee – Deadline

With voting set to open soon to determine the Oscar documentary shortlist, Flee continues to make a very strong case for recognition. The Neon...

Trending News

5 Yoga Poses for back pain

New Delhi: Back pain affects people of all age groups and is one of the world’s leading causes of disability. Back pain can...

Josephine Baker Enters France Pantheon – Deadline

Legendary Jazz Age performer and civil rights activist Josephine Baker made history today as the first Black woman to enter France’s hallowed Panthéon....

‘Flee’ Uses Animation To Tell Dramatic Story Of Gay Afghan Refugee – Deadline

With voting set to open soon to determine the Oscar documentary shortlist, Flee continues to make a very strong case for recognition. The Neon...

LeBron James Enters NBA health And Safety Protocols, Out For Tonight’s Game – Deadline

Lakers superstar LeBron James will miss tonight’s game vs. the Sacramento Kings because he has “entered the league’s health and safety protocols,” according...

‘The Infamous Frankie Lorde’ Books Getting Live-Action Movie Adaptation By Cyma Zarghami’s MiMO Studios & Trustbridge Global Media – Deadline

EXCLUSIVE: Former longtime Nickelodeon President Cyma Zarghami’s family and kids-focused MiMO Studio and Trustbridge Global Media are partnering to develop the The Infamous...

Rust Armorer’s Father Gives Police Pivotal Tip – Deadline

UPDATED with statement from Hannah Gutierrez-Reed) Santa Fe police may be a step closer to discovering where the live round fired last month...